No opioids during heart surgery? new study tests safer anesthesia for seniors
NCT ID NCT07360327
First seen Jan 22, 2026 · Last updated Jun 22, 2026 · Updated 24 times
Summary
This study compares opioid-free anesthesia using dexmedetomidine and ketamine to standard opioid-based anesthesia in 60 elderly patients undergoing elective coronary artery bypass surgery. The goal is to see if avoiding opioids leads to faster recovery, less confusion, and fewer breathing problems after surgery. Researchers will measure how quickly patients can be taken off the breathing tube and their mental status afterward.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dexmedetomidine and ketamine
What this could lead to
If successful, this could show that avoiding opioids during heart surgery leads to faster recovery and fewer complications like confusion or breathing problems.
What could go wrong
This is a small, early-phase study with only 60 participants, so results may not apply to everyone. The opioid-free approach may not control pain as well as standard care.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.