New combo therapy aims to control advanced breast cancer

NCT ID NCT05266105

First seen Jan 11, 2026 · Last updated May 14, 2026 · Updated 19 times

Summary

This early-stage trial tests a new drug, OP-1250, combined with the approved drug palbociclib in people with advanced or metastatic HR-positive, HER2-negative breast cancer. The main goals are to find the safest dose and check for side effects. About 60 adults whose cancer has spread will take part. This is not a cure, but aims to better control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Clinical Trial Site

    Waratah, New South Wales, 2298, Australia

  • Clinical Trial Site

    Westmead, New South Wales, 2145, Australia

  • Clinical Trial Site

    South Brisbane, Queensland, 4101, Australia

  • Clinical Trial Site

    Southport, Queensland, 4215, Australia

  • Clinical Trial Site

    Clayton, Victoria, 3168, Australia

  • Clinical Trial Site

    Frankston, Victoria, 3199, Australia

  • Clinical Trial Site

    Geelong, Victoria, 3220, Australia

  • Clinical Trial Site

    Nedlands, Western Australia, 6009, Australia

Conditions

Explore the condition pages connected to this study.