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Can online brain training sharpen thinking in schizophrenia?

NCT ID NCT05661448

Disease control Sponsor: Douglas Mental Health University Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 27, 2026 · Last updated Aug 28, 2026 · Updated 1 time

Summary

This trial tests two online programs designed to improve thinking skills in people with schizophrenia. One program focuses on cognitive remediation, helping participants build learning strategies and confidence. The other, metacognitive training, targets how people interpret information and make decisions. Researchers will compare the programs' effects on memory, attention, and daily functioning, and also train mental health practitioners to deliver them virtually.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Two online psychological programs: Action-Based Cognitive Remediation and MetaCognitive Training
What this could lead to
If effective, these online programs could offer a practical way to improve thinking and daily living skills for many people with schizophrenia.
What could go wrong
The trial is relatively small and early, and the benefits may not be large or lasting. Online delivery may not suit everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

192 people

The number who actually took part.

Started

Apr 2023

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of affective or non-affective psychosis or related disorder; * Follow-up and treatment by a clinician at one of the services mentioned above; * Participants symptomatically stable and capable of using the online platforms and participating in intervention groups, as judged by their primary clinicians (i.e., psychiatrist, case manager); * Participants must have access to a private space (i.e., a room where the participant can be alone) to ensure confidentiality for the group; * Participants must be able to nominate an emergency contact and to agree to allow researchers to contact their clinician and/or emergency services in the event of an emergency during study procedures. Exclusion Criteria: * Intellectual disability; * Hospitalization at the time of recruitment; * Inability to speak or read English or French; * High suicide risk as per evaluation.

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Conditions

The condition(s) this trial relates to.

Psychotic Disorders schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognition Schizophrenia

Contacts and locations

Locations

  • Douglas Mental Health University Institute

    Montreal, Quebec, H4H 1R3, Canada

  • Faculty of Medicine, University of British Columbia

    Vancouver, British Columbia, Canada

  • Institute of Mental Health Research, University of Ottawa

    Ottawa, Ontario, Canada

  • Kingston Health Sciences Centre, Queen's University

    Kingston, Ontario, Canada

  • Ontario Shoares Centre for Mental Health Sciences, University of Toronto

    Toronto, Ontario, Canada

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