New once-nightly drug could simplify narcolepsy treatment

NCT ID NCT04451668

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 25 times

Summary

This study tested a new once-nightly medication (FT218) for people with narcolepsy who experience excessive daytime sleepiness and sudden muscle weakness (cataplexy). It included 184 participants who either switched from a twice-nightly medication or were new to this type of treatment. The main goal was to check the long-term safety and tolerability of taking FT218 once per night.

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Contacts and locations

Locations

  • Advanced Respiratory and Sleep Medicine

    Huntersville, North Carolina, 28078, United States

  • Alpine Clinical Research Center

    Boulder, Colorado, 80301, United States

  • Baystate Medical Center

    Springfield, Massachusetts, 01199, United States

  • Bogan Sleep Consultants, LLC

    Columbia, South Carolina, 29201, United States

  • Brian Abaluck Sleep Medicine

    Malvern, Pennsylvania, 19355, United States

  • Comprehensive Sleep Medicine Associates

    Sugar Land, Texas, 77478, United States

  • Delta Waves, Inc.

    Colorado Springs, Colorado, 80918, United States

  • FL Pediatric Research Institute

    Winter Park, Florida, 32789, United States

  • Fort Wayne Neurological

    Fort Wayne, Indiana, 46804, United States

  • FutureSearch Trials of Neurology

    Austin, Texas, 78731, United States

  • Geisinger Medical Center

    Danville, Pennsylvania, 17822, United States

  • Helene A. Emsellem, MD PC

    Chevy Chase, Maryland, 20815, United States

  • Jodha Tishon Inc.

    Toronto, Ontario, M5S 3A3, Canada

  • Montefiore Sleep-Wake Disorders Center

    The Bronx, New York, 10467, United States

  • NeuroTrials Research Inc

    Atlanta, Georgia, 30328, United States

  • Northwest Houston Neurology

    Tomball, Texas, 77375, United States

  • Ohio Sleep Medicine Institute

    Dublin, Ohio, 43017, United States

  • Pulmonary Disease Specialists, PA

    Kissimmee, Florida, 34741, United States

  • SDS Clinical Trials

    Santa Ana, California, 92705, United States

  • Sleep Disorders Center of Alabama

    Birmingham, Alabama, 35213, United States

  • Sleep Management Institute Intrepid Research

    Cincinnati, Ohio, 45245, United States

  • Sleep Medicine Specialists of South Florida

    Miami, Florida, 33176, United States

  • Sleep Therapy & Research Center

    San Antonio, Texas, 78229-4849, United States

  • SleepCare Research Institute, Inc. d/b/a Clinical Research Institute

    Stockbridge, Georgia, 30281, United States

  • St. Luke's Hospital - Sleep Medicine and Research Center

    Chesterfield, Missouri, 63017, United States

  • Stanford Sleep Medicine

    Redwood City, California, 94063, United States

  • TPMG Clinical Research Williamsburg

    Williamsburg, Virginia, 23188, United States

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • West Perry Sound Health Center

    Parry Sound, Ontario, P2A 3A4, Canada

Conditions

Explore the condition pages connected to this study.