Study tests skipping radiation for Low-Risk breast cancer patients

NCT ID NCT07179744

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This study looks at whether women with a certain type of breast cancer (hormone-sensitive, HER2-negative, with 1-3 positive lymph nodes and a low RecurIndex score) can safely avoid radiation therapy to the lymph nodes. Researchers will follow 635 participants over time to see how many have their cancer come back. The goal is to find out if skipping this treatment is safe for low-risk patients.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this could show that some women with low-risk breast cancer can avoid unnecessary radiation, reducing side effects and treatment burden.
What could go wrong
This is an observational study, not a treatment trial, so it won't prove a new therapy works. Results may not apply to all patients, and there is a risk of recurrence if radiation is omitted.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

    RECRUITING

    Guangzhou, Guangdong, 510120, China

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