Dead bacteria may protect elderly from lung infections

NCT ID NCT07178002

Ongoing Prevention Sponsor: Fondazione Policlinico Universitario Campus Bio-Medico Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a pill made from dead bacteria (OM 85) can prevent lower respiratory tract infections in people aged 75+ living in nursing homes. Participants take the pill or a placebo for 10 days each month over 3 months. The goal is to see if the treatment reduces infections and related hospital visits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Bacterial lysate (OM 85)
What this could lead to: If it works, this could offer a simple way to reduce serious respiratory infections and hospitalizations in vulnerable older adults.
What could go wrong: This is a single Phase 4 trial with 360 participants. The effect may be small or not better than placebo, and results may not apply to all older adults.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

respiratory tract infectious disorder prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RESPIRATORY TRACT INFECTIONS (RTI)

Contacts and locations

Locations

Fondazione Policlinico Universitario Campus Bio Medico

Roma, Italia, 00128, Italy

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