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A simple breath test could spot lung infections in minutes

NCT ID NCT07685275

Not yet recruiting Diagnosis Sponsor: Hopital Foch Source: ClinicalTrials.gov ↗

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study investigates whether a real-time breath analysis device can quickly and non-invasively diagnose lower respiratory tract infections. Researchers will collect breath samples from 450 patients with suspected infections or chronic airway colonization and analyze volatile organic compounds (VOCs) using proton transfer reaction-mass spectrometry. The goal is to see if unique breath signatures can distinguish between infection, colonization, and no infection, and identify specific pathogens.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could provide a rapid, painless breath test to diagnose respiratory infections at the bedside, replacing slower or invasive methods.
What could go wrong
This is an early-stage diagnostic study; the breath signatures may not be accurate enough in real-world settings, and the device may not be widely adopted.

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Conditions

The condition(s) this trial relates to.

respiratory tract infectious disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RESPIRATORY TRACT INFECTIONS (RTI)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hôpital Foch

    Suresnes, 92150, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Necker

    Paris, 75015, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Raymond Poincaré

    Garches, 92380, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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