First test: how a new heart drug behaves in damaged livers

NCT ID NCT05481411

Summary

This early-stage study aimed to understand how a single dose of the experimental drug olpasiran is processed by the body in people with different levels of liver damage. It compared 25 participants with mild, moderate, or severe liver impairment to participants with normal liver function. The main goal was to check if the drug's behavior and safety profile changed based on liver health, which is a standard step before testing in larger patient groups.

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Contacts and locations

Locations

  • Inland Empire Clinical Trials, LLC

    Rialto, California, 92377, United States

  • Orlando Clinical Research Center

    Orlando, Florida, 32809, United States

  • The Texas Liver Institute, Inc.

    San Antonio, Texas, 78215, United States

Conditions

Explore the condition pages connected to this study.