First test: how a new heart drug behaves in damaged livers
NCT ID NCT05481411
First seen Nov 01, 2025 · Last updated Apr 06, 2026 · Updated 29 times
Summary
This early-stage study aimed to understand how a single dose of an experimental drug called olpasiran is processed by the body in people with different levels of liver damage. It compared 25 participants with mild, moderate, or severe liver impairment to participants with normal liver function. The main goal was to measure the drug's levels in the blood and check for safety to guide future dosing in patients with liver problems.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Inland Empire Clinical Trials, LLC
Rialto, California, 92377, United States
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Orlando Clinical Research Center
Orlando, Florida, 32809, United States
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The Texas Liver Institute, Inc.
San Antonio, Texas, 78215, United States
Conditions
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