New painkiller aims to make hysteroscopy safer and more comfortable
NCT ID NCT07713134
First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time
Summary
This trial compares a new painkiller called oliceridine to the standard drug sufentanil for women undergoing hysteroscopy, a procedure to look inside the uterus. The goal is to see if oliceridine provides effective pain control with fewer side effects like nausea or breathing problems. The study includes 225 women aged 18 to 60 who are in good health.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- oliceridine, a biased μ-opioid receptor agonist, compared with sufentanil
- What this could lead to
- If oliceridine works well, it could offer a safer alternative for pain relief during minor surgical procedures, with fewer side effects like nausea or breathing problems.
- What could go wrong
- This is a single trial with 225 participants, so results may not apply to everyone. Oliceridine is still experimental, and its safety and effectiveness compared to standard drugs are not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
225 people
The number who actually took part.
- Started
-
Aug 2025
- Finished
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Jun 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 60 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. voluntary signing of the anesthesia informed consent form; 2. stable vital signs; 3. age between 18 and 60years; 4. American Society of Anesthesiologists (ASA) physical status I or II; and 5. body mass index (BMI) \<30 kg/m² Exclusion Criteria: 1. inability or unwillingness to sign the informed consent form; 2. known allergy to the study drug; 3. uncontrolled hypertension or diabetes mellitus; 4. significant central nervous system disease; 5. diagnosed psychiatric disorders; 6. use of anxiolytics, antidepressants, hypnotics, or sedatives within the past three months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Tangshan Maternal and Child Health Hospital, Tangshan, Hebei 063000
Tangshan, Hebei, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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