New hope for chinese men with tough prostate cancer: targeted drug takes on standard care

NCT ID NCT05457257

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study compares the targeted drug olaparib to two standard hormone therapies (enzalutamide or abiraterone) in Chinese men with advanced prostate cancer that has stopped responding to hormone treatment and who have BRCA1/2 gene mutations. The goal is to see if olaparib can delay cancer growth better than the usual options. About 43 men will participate, and the study tracks how long their cancer stays under control.

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Conditions

The condition(s) this trial relates to.

castration-resistant prostate carcinoma metastatic prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Beijing, 100050, China

  • Research Site

    Bengbu, 233004, China

  • Research Site

    Changsha, 410008, China

  • Research Site

    Changsha, 410013, China

  • Research Site

    Chengdu, 610000, China

  • Research Site

    Chongqing, 408099, China

  • Research Site

    Fuzhou, 350005, China

  • Research Site

    Guangzhou, 510060, China

  • Research Site

    Guangzhou, 510180, China

  • Research Site

    Hangzhou, 310003, China

  • Research Site

    Hangzhou, 310009, China

  • Research Site

    Hangzhou, 310014, China

  • Research Site

    Hefei, 230601, China

  • Research Site

    Jiaxing, 314001, China

  • Research Site

    Jinan, 250012, China

  • Research Site

    Jinan, 250021, China

  • Research Site

    Jining, 272029, China

  • Research Site

    Kunming, 650101, China

  • Research Site

    Lanzhou, 730030, China

  • Research Site

    Linyi, 276000, China

  • Research Site

    Nanchang, 330006, China

  • Research Site

    Nantong, 226361, China

  • Research Site

    Ningbo, 315010, China

  • Research Site

    Shanghai, 200002, China

  • Research Site

    Shanghai, 200032, China

  • Research Site

    Shenyang, 110004, China

  • Research Site

    Suzhou, 215004, China

  • Research Site

    Taiyuan, 030000, China

  • Research Site

    Tianjin, 300060, China

  • Research Site

    Wanzhou, 404000, China

  • Research Site

    Wuhan, 430022, China

  • Research Site

    Wuxi, 214002, China

  • Research Site

    Wuxi, 214023, China

  • Research Site

    Xi'an, 710077, China

  • Research Site

    Zhengzhou, 450052, China