Promising early trial combines targeted drug with radiation for rare sarcoma

NCT ID NCT02787642

First seen Feb 26, 2026 · Last updated May 13, 2026 · Updated 13 times

Summary

This early-phase study tested the safety of adding the drug olaparib to standard radiation therapy for people with advanced soft-tissue sarcoma that could not be removed by surgery. 41 adults took part. The main goals were to find the highest safe dose of olaparib and to see how many patients had their tumor shrink or stay stable after 6 months. The results help guide future research on this combination.

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Contacts and locations

Locations

  • Centre Léon Bérard

    Lyon, 69373, France

  • Institut Bergonié

    Bordeaux, 33076, France

  • Institut Claudius Regaud - IUCT

    Toulouse, 31052, France

  • Institut du Cancer de Montpellier

    Montpellier, 34298, France

Conditions

Explore the condition pages connected to this study.