New drug combo shows promise for tough prostate cancer

NCT ID NCT03787680

First seen Mar 27, 2026 · Last updated May 05, 2026 · Updated 7 times

Summary

This study tests whether combining two drugs, olaparib and AZD6738, can shrink tumors or lower PSA levels in men with advanced prostate cancer that no longer responds to hormone therapy. About 49 men with metastatic castration-resistant prostate cancer will receive the drug combination. The goal is to see how well the treatment works and how safe it is.

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Contacts and locations

Locations

  • University of Michigan Hospital

    Ann Arbor, Michigan, 48109, United States

  • University of Virginia Health System

    Charlottesville, Virginia, 22908, United States

  • Wayne State University/Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

Conditions

Explore the condition pages connected to this study.