Massive MS registry aims to decode why some patients worsen faster than others

NCT ID NCT03603457

Ongoing Knowledge-focused Sponsor: EDMUS Foundation Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This observational study follows thousands of people with multiple sclerosis (MS) over many years to identify factors that predict how the disease will progress. Researchers collect detailed clinical data, MRI scans, and quality-of-life questionnaires from participants treated at specialized MS centers in France. The goal is to build personalized prognostic tools that help doctors decide when to start or change treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could lead to better tools for predicting how multiple sclerosis will progress in individual patients, helping doctors tailor treatments earlier.
What could go wrong: This is an observational study, not a treatment trial, so it cannot prove cause and effect. The findings may take years to translate into practical tools.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE SCLEROSIS

Contacts and locations

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Locations

CHI de Poissy-Saint-Germain-en-Laye

Poissy, France
CHU Pitié-Salpétrière

Paris, France
CHU Saint-Antoine

Paris, France
CHU de Besançon

Besançon, France
CHU de Bordeaux

Bordeaux, France
CHU de Caen

Caen, France
CHU de Clermont-Ferrand

Clermont-Ferrand, France
CHU de Créteil

Créteil, France
CHU de Dijon

Dijon, France
CHU de Fort-de-France

Fort-de-France, Martinique
CHU de Grenoble

Grenoble, France
CHU de Lille

Lille, France
CHU de Limoges

Limoges, France
CHU de Lyon

Lyon, France
CHU de Montpellier

Montpellier, France
CHU de Nancy

Nancy, France
CHU de Nantes

Nantes, France
CHU de Nice

Nice, France
CHU de Nîmes

Nîmes, France
CHU de Poitiers

Poitiers, France
CHU de Rennes

Rennes, France
CHU de Strasbourg

Strasbourg, France
CHU de Toulouse

Toulouse, France
CHU de Tours

Tours, France
Fondation Rothschild

Paris, France

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