New Dual-Action antibody tested for Tough-to-Treat blood cancers
NCT ID NCT02290951
Summary
This early-stage study tested the safety and initial effectiveness of a new drug called odronextamab in 200 adults with advanced non-Hodgkin lymphoma or chronic lymphocytic leukemia. The drug is designed to attach to cancer cells and the immune system to help the body fight the cancer. The study tested different doses given by IV and injection to find the safest amount and see if it could shrink tumors in patients who had few other treatment options.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Assuta Ashdod University Hospital
Ashdod, Southern District, 7747629, Israel
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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CHU Hôpital Lyon Sud
Lyon, 69495, France
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Centre Henri Becquerel
Rouen, Haute-Normandie, 76038, France
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Dana Farber Cancer Institute (Massachusetts General Hospital and Beth Israel)
Boston, Massachusetts, 02215, United States
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H. Lee Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Hadassah Medical Center
Jerusalem, Jerusalem, 9112001, Israel
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Institut Gustave Roussy
Villejuif, Île-de-France Region, 94800, France
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Lady Davis Carmel Medical Center
Haifa, 3436212, Israel
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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Meir Medical Center
Kfar Saba, Central District, 44281, Israel
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Rambam Health Care Campus - Hematology and Bone Marrow Transplantation Institute
Haifa, 3109601, Israel
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Royal Cornwall Hospitals NHS Trust
Truro, Cornwall, tr1 3lq, United Kingdom
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Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08901, United States
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Stanford University
Stanford, California, 94305, United States
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The Chaim Sheba Medical Center
Tel-Hashomer, Central District, 5265601, Israel
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The Christie NHS Foundation Trust
Manchester, M20 4BX, United Kingdom
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Universitatsklinikum Wurzburg
Würzburg, Bavaria, 97080, Germany
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University of California, Irvine
Orange, California, 92868, United States
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Weill Cornell Medical College
New York, New York, 10065, United States
Conditions
Explore the condition pages connected to this study.