New hope for tough lymphoma: experimental drug faces standard care in phase 3 showdown
NCT ID NCT06230224
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests an experimental drug, odronextamab, in people with aggressive B-cell non-Hodgkin lymphoma that has come back or no longer responds to treatment. About 216 participants will receive either the new drug or standard therapy to compare safety, effectiveness, and quality of life. The goal is to see if odronextamab can better control the cancer and delay its progression.
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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A Beneficencia Portuguesa de Sao Paulo, Oncology House
São Paulo, 01321000, Brazil
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Amaral Carvalho Hospital
Jaú, São Paulo, 17210-080, Brazil
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Ankara University Faculty of Medicine
Mamak, Ankara, 06620, Turkey (Türkiye)
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Asan Medical Center
Seoul, 05505, South Korea
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Casa de Saude Santa Marcelina
São Paulo, 08270-070, Brazil
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Centro Gaucho Integrado
Porto Alegre, Rio Grande do Sul, 90110-270, Brazil
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Chang Gung Memorial Hospital - Linkou Branch
Taoyuan, Hunan Province, 33305, Taiwan
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Chang Gung Memorial Hospital Kaohsiung
Kaohsiung City, 83301, Taiwan
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Changhua Christian Hospital
Changhua, 500-06, Taiwan
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Chiang Mai University
Chiang Mai, 50200, Thailand
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Chulalongkorn University
Bangkok, 10330, Thailand
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Clinica Alemana de Santiago
Santiago, Santiago Metropolitan, 7650620, Chile
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Clinica Imbanaco
Cali, Valle del Cauca Department, 760042, Colombia
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Clinica Universidad de Navarra- Pamplona
Pamplona, 31008, Spain
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Coltea Clinical Hospital
Bucharest, Bucharest, 030141, Romania
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Debreceni Egyetem
Debrecen, Hajdú-Bihar, 4032, Hungary
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Dong-A University Hospital
Busan, 49201, South Korea
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Ege University
Izmir, 35100, Turkey (Türkiye)
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Ensino e Terapia de Inovacao Clinica Amo (Etica)
Salvador, Estado de Bahia, 41950-640, Brazil
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Fundacion Arturo Lopez Perez
Santiago, Santiago Metropolitan, 7500921, Chile
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Fundaleu - Fundacion Para Combatir La Leucemia
Ciudad Autonoma de Buenos Aires, Buenos Aires, C1114AAN, Argentina
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Gachon University Gil Medical Center
Incheon, Namdong-Gu, 21565, South Korea
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Gazi University
Ankara, Central Anatolia, 06100, Turkey (Türkiye)
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Hospital Aleman
Ciudad Autonoma de Buenos Aires, Buenos Aires, 1118, Argentina
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Hospital Alta Complejidad El Cruce
San Juan Bautista, Buenos Aires, B1888AAE, Argentina
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Hospital Ampang
Kuala Lumpur, Selangor, 68000, Malaysia
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Hospital Britanico de Buenos Aires
Ciudad Autonoma de Buenos Aires, Buenos Aires, 1280, Argentina
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Hospital Erasto Gaertner
Curitiba, Paraná, 81520-060, Brazil
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Hospital Italiano de Buenos Aires
Ciudad Autonoma de Buenos Aires, Buenos Aires, C1199ABB, Argentina
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Hospital Italiano de La Plata
La Plata, Buenos Aires, B1900AUR, Argentina
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Hospital Pablo Tobon Uribe
Medellín, Antioquia, 050034, Colombia
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Hospital Privado Universitario de Cordoba
Córdoba, X5016KEH, Argentina
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Hospital Queen Elizabeth
Kota Kinabalu, Sabah, 88586, Malaysia
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Hospital Santa Izabel - Santa Casa de Misericordia da Bahia
Salvador, Estado de Bahia, 40050-410, Brazil
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Hospital Sao Rafael
Salvador, Estado de Bahia, 40285-000, Brazil
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Hospital Sirio Libanes
São Paulo, 01308-050, Brazil
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Hospital Sirio Libanes Brasilia
Brasília, Federal District, 70200-730, Brazil
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Hospital Sultanah Aminah Jhor Bahru
Johor Bahru, Johor, 80100, Malaysia
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Hospital Universitari Son Espases
Palma, Balearic Islands, 07120, Spain
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Hospital Universitario Ramon y Cajal
Madrid, 28034, Spain
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Hospital das Clinicas, Faculty of Medicine, University of Sao Paulo
São Paulo, 05403-000, Brazil
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Hospital de Clinicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
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Instituto Alexander Fleming
Ciudad Autonoma de Buenos Aires, Buenos Aires, 1426, Argentina
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Instituto D'Or De Pesquisa e Ensino
São Paulo, 04501-000, Brazil
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Instituto Nacional de Cancer Jose Alencar Gomes da Silva
Rio de Janeiro, 20231050, Brazil
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Instituto Valenciano de Oncologia
Valencia, 46009, Spain
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Ion Chiricuta Oncology Institute
Cluj-Napoca, Cluj, 400015, Romania
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Istanbul University
Istanbul, 34418, Turkey (Türkiye)
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Jeonbuk National University Hospital
Jeonju, Jeollabuk-do, 54907, South Korea
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Kaohsiung Medical University Hospital
Kaohsiung City, 80756, Taiwan
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Keimyung University Dongsan Hospital
Daegu, 42601, South Korea
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Khon Kaen University
Khon Kaen, 40002, Thailand
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National Cancer Center
Gyeonggi-do, Gyeonggi-do, 10408, South Korea
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National Cheng Kung University Hospital
Tainan, 704, Taiwan
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National Taiwan University Hospital
Taipei, 10002, Taiwan
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National University Hospital Singapore
Singapore, 119074, Singapore
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Olivia Newton John Cancer Wellness & Research Centre
Heidelberg, Victoria, 3084, Australia
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Ondokuz Mayıs University
Samsun, 55270, Turkey (Türkiye)
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Princess Alexandra Hospital
Woolloongabba, Queensland, 4102, Australia
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Pusan National University Hospital
Busan, 49241, South Korea
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Pusan National University Yangsan Hospital
Yangsan, Gyeongsangnam-do, 50612, South Korea
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Sakarya University Medical Faculty
Sakarya, 54290, Turkey (Türkiye)
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Sanatorio Allende
Córdoba, X5000JHQ, Argentina
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Sbu Dr.A.Y. Ankara Onkoloji Suam
Ankara, 06100, Turkey (Türkiye)
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Semmelweis University
Budapest, 1088, Hungary
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Seoul St Marys Hospital
Seoul, 06591, South Korea
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Show Chwan Memorial Hospital
Changhua, 50008, Taiwan
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Sriraj Hospital
Bangkok, 10700, Thailand
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St. Vincent Hospital - The Catholic University of Korea
Suwon, Gyeonggi-do, 16247, South Korea
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Subang Jaya Medical Center
Subang Jaya, Selangor, 47500, Malaysia
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Taichung General Veterans Hospital
Taichung, 40705, Taiwan
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Tekirdag Namik Kemal University Hospital
Tekirdağ, Suleymanpasa, 59100, Turkey (Türkiye)
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Tri-Service General Hospital
Taipei, 11490, Taiwan
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Ulsan University Hospital
Ulsan, 44033, South Korea
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University Malaya Medical Centre
Kuala Lumpur, Kuala Lumpur, 59100, Malaysia
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University of Pecs
Pécs, Baranya, 7624, Hungary
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Uopeccan Hospital do Cancer de Cascavel
Cascavel, Paraná, 85806-300, Brazil
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VKV American Hopital
Istanbul, 34365, Turkey (Türkiye)
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VM Medical Park Mersin Hospital
Mezitli, Mersin, 33200, Turkey (Türkiye)
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Yeouido St. Marys Hospital
Seoul, 07345, South Korea
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Zonguldak Bulent Ecevit University
Zonguldak, 67600, Turkey (Türkiye)