MS drug holiday: study tests if early patients can stop treatment without relapse
NCT ID NCT05285891
First seen Jan 04, 2026 · Last updated May 16, 2026 · Updated 25 times
Summary
This study looks at whether people with early relapsing multiple sclerosis (MS) can stop taking the drug ocrelizumab after two years and still stay relapse-free. About 123 participants will receive the drug for two years, then be randomly assigned to continue the drug or switch to a placebo for another two years. The goal is to see if early treatment can lead to lasting remission without ongoing medication.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
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Locations
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Icahn School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10007, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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MedStar Georgetown University Hospital
RECRUITINGWashington D.C., District of Columbia, 20007, United States
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Oklahoma Medical Research Foundation
RECRUITINGOklahoma City, Oklahoma, 73104, United States
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The University of Texas Health Science Center at Houston, McGovern Medical School
RECRUITINGHouston, Texas, 77030, United States
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University of Massachusetts Memorial Medical Center
RECRUITINGWorcester, Massachusetts, 01655, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pennsylvania, Perelman School of Medicine
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Contact Email: •••••@•••••
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University of Rochester Medical Center
RECRUITINGRochester, New York, 14627, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Virginia Commonwealth University School of Medicine
RECRUITINGRichmond, Virginia, 23298, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yale School of Medicine
RECRUITINGNew Haven, Connecticut, 06510, United States
Contact
Contact Email: •••••@•••••
Conditions
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