New dissolving nasal dressing could improve sinus surgery recovery

NCT ID NCT07286201

ENROLLING_BY_INVITATION Disease control Sponsor: Polyganics BV Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a new biodegradable nasal dressing that slowly releases a steroid (mometasone furoate) to a standard steroid-releasing stent, both used after sinus surgery. About 110 adults with chronic sinusitis (with or without nasal polyps) will receive the new dressing in one nostril and the standard stent in the other. The goal is to see if the new dressing is as safe and effective at promoting wound healing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: mometasone furoate
What this could lead to: If successful, this could offer a safer, absorbable alternative to current steroid stents for improving healing after sinus surgery.
What could go wrong: This is an early-stage, non-randomized comparison with only 110 participants. The dressing may not prove superior or could have unexpected side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic rhinosinusitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC RHINOSINUSITIS (CRS) CHRONIC RHINOSINUSITIS (CRS) WITH AND WITHOUT NASAL POLYPS

Contacts and locations

Locations

Centers for Advanced ENT Care

Towson, Maryland, 21204, United States
Colorado ENT & Allergy

Colorado Springs, Colorado, 80923, United States
ENT Allergy & Associates

Puyallup, Washington, 98374, United States
Emory University

Atlanta, Georgia, 30308, United States
Louisiana State University Health at Shreveport

Shreveport, Louisiana, 71103, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Ogden Clinic

Ogden, Utah, 84403, United States
University of Illinois at Chicago

Chicago, Illinois, 60612, United States
University of Texas Health

Houston, Texas, 77030, United States

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