New drug tested to stop dangerous transplant complication

NCT ID NCT02867384

Summary

This study tested whether a drug called obinutuzumab could prevent chronic Graft-vs-Host Disease (cGVHD) in patients who received a stem cell transplant. cGVHD is a serious condition where the donor's immune cells attack the recipient's body. In this trial, 181 adult transplant patients were randomly assigned to receive either obinutuzumab or a placebo to see if the drug reduced the need for steroid treatment for cGVHD.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Huntsman Cancer Institute

    Salt Lake City, Utah, 84112, United States

  • Masonic Cancer Center

    Minneapolis, Minnesota, 55455, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Stanford University

    Palo Alto, California, 94305, United States

Conditions

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