New shot shows promise for shedding pounds in Mid-Stage trial

NCT ID NCT07281495

First seen Jan 05, 2026 · Last updated May 11, 2026 · Updated 24 times

Summary

This study tests an investigational drug called taldefgrobep alfa to see if it helps adults with overweight or obesity lose weight. About 150 participants will receive either the drug or a placebo by injection for 24 weeks, with an option to continue in an open-label extension. The main goal is to measure the percentage change in total body weight from the start to week 24.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Site-001

    Chula Vista, California, 91911, United States

  • Site-002

    Fargo, North Dakota, 58104, United States

  • Site-003

    Springfield, Missouri, 65807, United States

  • Site-004

    Arlington, Virginia, 22205, United States

  • Site-005

    Austin, Texas, 78745, United States

  • Site-006

    City of Saint Peters, Missouri, 63303, United States

  • Site-007

    Chicago, Illinois, 60625, United States

  • Site-008

    Palm Springs, Florida, 33461, United States

  • Site-009

    Metairie, Louisiana, 70006, United States

  • Site-010

    Baton Rouge, Louisiana, 70808, United States

  • Site-011

    Sacramento, California, 95821, United States

  • Site-012

    McKinney, Texas, 75069, United States

  • Site-013

    San Antonio, Texas, 78229, United States

  • Site-014

    Montclair, California, 97163, United States

  • Site-015

    St. Petersburg, Florida, 33704, United States

  • Site-016

    Indianapolis, Indiana, 46254, United States

  • Site-017

    North Charleston, South Carolina, 29405, United States

  • Site-018

    Tustin, California, 92780, United States

  • Site-019

    Monroe, North Carolina, 28112, United States

  • Site-020

    Orlando, Florida, 32804, United States

Conditions

Explore the condition pages connected to this study.