Experimental cell therapy takes on Tough-to-Treat MS

NCT ID NCT07139743

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 21 times

Summary

This early-stage study tests whether a new cell therapy called obe-cel is safe for people with progressive multiple sclerosis (MS) that hasn't responded to other treatments. About 18 adults will receive chemotherapy followed by a single infusion of obe-cel, then be closely monitored for side effects and any signs of improvement over two years. The goal is to see if this approach can control the disease, not cure it.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PROGRESSIVE MULTIPLE SCLEROSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Addenbrooke's Hospital

    RECRUITING

    Cambridge, United Kingdom

    Contact

  • Hospital Universitari i Politecnic La Fe de Valencia

    RECRUITING

    Valencia, Spain

    Contact

  • Hospital Universitario Vall d'Hebron - PPDS

    ACTIVE_NOT_RECRUITING

    Barcelona, Spain

  • Royal Hallamshire Hospital

    RECRUITING

    Sheffield, United Kingdom

    Contact

  • Stanford University

    NOT_YET_RECRUITING

    Redwood City, California, 94063, United States

    Contact

  • The National Hospital for Neurology & Neurosurgery

    RECRUITING

    London, United Kingdom

    Contact Email: •••••@•••••

    Contact

  • Western General Hospital Edinburgh - PPDSE Edinburgh

    RECRUITING

    Edinburgh, United Kingdom

    Contact

Conditions

Explore the condition pages connected to this study.