Could a simple supplement ease sickle cell symptoms?
NCT ID NCT05791591
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a nutraceutical supplement called NUV001 in 168 adults with sickle cell disease. Participants took either an immediate-release or gastro-resistant version of NUV001, or a placebo, daily for 90 days. The main goal was to check safety and tolerability, with early looks at blood markers and patient-reported outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
NUV001 (a nutraceutical supplement)
What this could lead to
If it works, this could point toward a safe, daily supplement to help manage sickle cell disease symptoms alongside standard care.
What could go wrong
This is a small, early pilot study focused on safety, not proof of effectiveness. The supplement may show no benefit over placebo.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SICKLE CELL DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Aman Hospital and Research Center
Vadodara, Gujarat, Vadodara-390021, India
-
Arihant Multispeciality Hospital
Nagpur, India
-
Index Medical College
Indore, India
-
Kingsway Hospital
Nagpur, Maharashtra, Nagpur-440001, India
-
NRSMC Hospital
Kolkata, India
-
Sai Krupa Hospital & Research Centre
Ahmedabad, India
-
Shalinitai Meghe Hospital & Research Centre
Nagpur, India
-
Shivam Hospital
Ahmedabad, 380008, India
-
Thalassemia & Sickle Cell Society
Hyderabad, India