Nurses could be key to expanding HIV prevention in rural america

NCT ID NCT07346508

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether nurses, instead of doctors, can safely and effectively give long-acting HIV prevention shots in rural public health clinics. About 250 adults at risk for HIV will take part across several clinics in Missouri. The goal is to see if this nurse-driven approach helps more people access and stay on this prevention method, especially in areas with few healthcare providers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Long-acting injectable cabotegravir (LAI-CAB) for HIV pre-exposure prophylaxis (PrEP)
What this could lead to
If successful, this nurse-driven model could make long-acting HIV prevention widely available in rural and underserved communities, reducing new HIV infections.
What could go wrong
This is an early implementation study, not a large-scale trial, so results may not apply everywhere. The approach depends on nurse training and local resources, which could limit success in other settings.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

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