New cancer drug shows promise in early trial for advanced tumors

NCT ID NCT03829254

First seen Jan 12, 2026 · Last updated May 17, 2026 · Updated 20 times

Summary

This study is testing a new drug called NUC-7738 in people with advanced solid tumors or lymphoma that have not responded to other treatments. The goal is to find a safe dose and see if the drug can shrink tumors, either alone or combined with another drug (pembrolizumab). About 135 participants will receive the drug by IV, and researchers will monitor side effects and tumor changes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cambridge University Hospitals NHS Foundation Trust (Addenbrookes Hospital)

    RECRUITING

    Cambridge, CB2 0QQ, United Kingdom

  • Edinburgh Cancer Centre, Western General Hospital

    RECRUITING

    Edinburgh, EH4 2XU, United Kingdom

  • Freeman Hospital

    RECRUITING

    Newcastle, NE7 7DN, United Kingdom

  • Lancashire Teaching Hospitals NHS Foundation Trust, Royal Preston Hospital

    RECRUITING

    Preston, PR2 9HT, United Kingdom

  • Oxford University Hospitals NHS Foundation Trust

    RECRUITING

    Oxford, OX3 9DU, United Kingdom

  • The Beatson West of Scotland Cancer Centre

    RECRUITING

    Glasgow, G12 0TN, United Kingdom

  • The Christie NHS Foundation Trust

    RECRUITING

    Manchester, M20 4BX, United Kingdom

  • The Royal Marsden NHS Foundation Trust

    RECRUITING

    London, SW3 6JJ, United Kingdom

  • University College London Hospital

    RECRUITING

    London, NW1 2PG, United Kingdom

Conditions

Explore the condition pages connected to this study.