Gene therapy aims to stop painful swelling attacks in rare disease

NCT ID NCT05120830

First seen Apr 01, 2026 · Last updated May 13, 2026 · Updated 9 times

Summary

This study tests a new treatment called NTLA-2002 for adults with hereditary angioedema (HAE), a condition that causes sudden, painful swelling attacks. The therapy uses gene-editing to reduce a protein that triggers attacks. Researchers are checking safety and how well it works in 37 participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Clinical Trial Site

    Campbelltown, Australia

  • Clinical Trial Site

    Grenoble, France

  • Clinical Trial Site

    Lille, France

  • Clinical Trial Site

    Paris, France

  • Clinical Trial Site

    Berlin, Germany

  • Clinical Trial Site

    Frankfurt, Germany

  • Clinical Trial Site

    Amsterdam, Netherlands

  • Clinical Trial Site

    Auckland, New Zealand

  • Clinical Trial Site

    Cambridge, United Kingdom

Conditions

Explore the condition pages connected to this study.