Experimental drug aims to rebuild immune defenses in rare disease

NCT ID NCT05600920

First seen Jan 08, 2026 · Last updated May 07, 2026 · Updated 19 times

Summary

This study tests a new drug called NT-I7 in people with idiopathic CD4 lymphopenia (ICL), a rare condition where the body lacks key immune cells called CD4 T cells. The goal is to see if NT-I7 can safely increase these cells and help prevent severe infections. About 60 adults aged 18 to 75 will receive three injections over several months, with close monitoring for side effects and immune changes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.