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Nezelof syndrome

MONDO:0009451

Also known as: Nezelof syndrome, Nezelof's syndrome, T-lymphocyte deficiency, immune defect due to absence Of Thymus, immune defect due to absence of THYMUS, thymic aplasia

2 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Hereditary disease (176) Immune system disorder (148) Immunodeficiency disease (54) Human disease (14) T-cell immunodeficiency (4) Disease of genetic or genomic mechanism (2) Congenital T-cell immunodeficiency (0) Disease by body system or component (0) Disease by etiologic mechanism (0)
Trials to join now! 1 Completed 1
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  • Experimental drug aims to rebuild immune defenses in rare disorder

    Disease control Recruiting now

    This study tests an experimental drug called NT-I7 in people with idiopathic CD4 lymphopenia (ICL), a condition where low CD4 immune cells lead to severe infections and other diseases. The goal is to see if NT-I7 can safely increase CD4 cell counts. About 60 adults aged 18–75 wil…

    Phase: PHASE1, PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control

    Last updated Jul 26, 2026 00:00 UTC

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