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New drug shows promise for swallowing disorder

NCT ID NCT06598462

Ongoing Disease control Sponsor: Uniquity One (UNI) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental drug called NSI-8226 (solrikitug) in adults with eosinophilic esophagitis, a condition that causes trouble swallowing due to inflamed esophagus. About 184 participants will receive either the drug or a placebo to see if it reduces inflammation and improves swallowing symptoms. The goal is to find a safer, more effective treatment for this chronic condition.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

eosinophilic esophagitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EOSINOPHILIC ESOPHAGITIS (EOE)

Contacts and locations

Locations

  • Research Site 1001

    Jacksonville, Florida, 32256, United States

  • Research Site 1002

    Ogden, Utah, 84405, United States

  • Research Site 1003

    Tucson, Arizona, 85715, United States

  • Research Site 1004

    Boston, Massachusetts, 02111, United States

  • Research Site 1005

    Irvine, California, 92618, United States

  • Research Site 1006

    Plymouth, Minnesota, 55446, United States

  • Research Site 1007

    Boise, Idaho, 83706, United States

  • Research Site 1008

    Houston, Texas, 77494, United States

  • Research Site 1012

    Columbus, Ohio, 43213, United States

  • Research Site 1013

    Wyoming, Michigan, 49519, United States

  • Research Site 1014

    Dallas, Texas, 75230, United States

  • Research Site 1015

    San Diego, California, 92120, United States

  • Research Site 1016

    Reno, Nevada, 89511, United States

  • Research Site 1017

    Sandy City, Utah, 84092, United States

  • Research Site 1018

    Glendale, Arizona, 85306, United States

  • Research Site 1018

    Peoria, Arizona, 85306, United States

  • Research Site 1019

    Salt Lake City, Utah, 84132, United States

  • Research Site 1020

    Harrisburg, Pennsylvania, 17110, United States

  • Research Site 1021

    High Point, North Carolina, 27265, United States

  • Research Site 1022

    Iowa City, Iowa, 52242, United States

  • Research Site 1023

    Englewood, California, 90301, United States

  • Research Site 1024

    Ann Arbor, Michigan, 48109, United States

  • Research Site 1026

    Chapel Hill, North Carolina, 27599, United States

  • Research Site 1027

    Cromwell, Connecticut, 06416, United States

  • Research Site 1030

    Philadelphia, Pennsylvania, 19104, United States

  • Research Site 1032

    Chevy Chase, Maryland, 20815, United States

  • Research Site 1033

    Topeka, Kansas, 66606, United States

  • Research Site 1034

    Aurora, Colorado, 80045, United States

  • Research Site 1036

    Pearland, Texas, 77584, United States

  • Research Site 1037

    Scottsdale, Arizona, 85258, United States

  • Research Site 1039

    Dothan, Alabama, 36305, United States

  • Research Site 1040

    Inverness, Florida, 34452, United States

  • Research Site 1041

    Rockwell, Texas, 75032, United States

  • Research Site 1042

    Creve Coeur, Missouri, 63141, United States

  • Research Site 1043

    Jackson, New Jersey, 08527, United States

  • Research Site 1045

    Freehold, New Jersey, 07728, United States

  • Research Site 1048

    Glenview, Illinois, 60026, United States

  • Research Site 1049

    Miami, Florida, 33155, United States

  • Research Site 1101

    Parkville, Victoria, 3010, Australia

  • Research Site 1102

    Fitzroy, Victoria, 3065, Australia

  • Research Site 1103

    South Brisbane, Queensland, 4101, Australia

  • Research Site 1106

    Box Hill, Victoria, 3128, Australia

  • Research Site 1107

    Woolloongabba, Queensland, 4102, Australia

  • Research Site 1107

    Woolloongabba, QLD 4102, Australia

  • Research Site 1108

    Newcastle, New South Wales, 02111, Australia

  • Research Site 1109

    Murdoch, Western AUS, 6050, Australia

  • Research Site 1110

    Maroochydore, Queensland, 4558, Australia

  • Research Site 1111

    Maroochydore, QLD 4558, Australia

  • Research Site 1151

    Leuven, VLG, 3000, Belgium

  • Research Site 1152

    Bruges, 8310, Belgium

  • Research Site 1153

    Tournai, 7500, Belgium

  • Research Site 1201

    Warsaw, 04-501, Poland

  • Research Site 1202

    Szczecin, 04-501, Poland

  • Research Site 1203

    Warsaw, 00-189, Poland

  • Research Site 1204

    Warsaw, 04-141, Poland

  • Research Site 1205

    Tychy, 43-100, Poland

  • Research Site 1206

    Warsaw, 02-781, Poland

  • Research Site 1207

    Lodz, 90-752, Poland

  • Research Site 1252

    Milan, Ca'Granada, 20122, Italy

  • Research Site 1253

    Padova, IT, 35128, Italy

  • Research Site 1255

    Roma, IT, 00168, Italy

  • Research Site 1256

    Campobasso, IT, 86100, Italy

  • Research Site 1258

    Verona, 37134, Italy

  • Research Site 1259

    Pieve Emanuele, MI, 20072, Italy

  • Research Site 1302

    Rotterdam, 3000, Netherlands

  • Research Site 1303

    Maastricht, AZ, 6202, Netherlands

  • Research Site 1351

    Tomelloso, 13700, Spain

  • Research Site 1352

    Madrid, 28040, Spain

  • Research Site 1353

    Madrid, 28006, Spain

  • Research Site 1354

    Barcelona, 08022, Spain

  • Research Site 1402

    Zurich, 8044, Switzerland

  • Research Site 1551

    Whitechapel, London, E1 1BB, United Kingdom

  • Research Site 1553

    London, Tooting, SW17 0GT, United Kingdom

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