Lung cancer study explores new drug combo after treatment fails

NCT ID NCT00596648

First seen Jan 20, 2026 · Last updated May 13, 2026 · Updated 15 times

Summary

This study tested a drug called cabozantinib, given alone or with another drug called erlotinib, in 92 adults with advanced non-small cell lung cancer. Participants had already tried erlotinib and their cancer had gotten worse. The goal was to find a safe dose and see if the combination could shrink tumors. The study was completed, and results help guide future treatment options for this type of lung cancer.

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Contacts and locations

Locations

  • Case Western Reserve University

    Cleveland, Ohio, 44106, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Georgetown University/Lombardi Comprehensive Cancer Center

    Washington D.C., District of Columbia, 20007, United States

  • Katmai Oncology Group

    Anchorage, Alaska, 99508, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Park Nicollet Institute

    Saint Louis Park, Minnesota, 55416, United States

  • Stanford University Medical Center

    Palo Alto, California, 94305, United States

  • Summit Medical Group

    Berkeley Heights, New Jersey, 07922, United States

  • Swedish Cancer Institute

    Seattle, Washington, 98104, United States

  • University of California, Davis

    Sacramento, California, 95817, United States

  • University of Chicago Medical Center

    Chicago, Illinois, 60637, United States

  • University of Washington/ Seattle Cancer Care Alliance

    Seattle, Washington, 98109, United States

  • Yale University School of Medicine

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.