New combo therapy shows promise for tough lung cancer cases

NCT ID NCT00596648

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a drug called cabozantinib, either alone or with another drug (erlotinib), in 92 people with advanced non-small cell lung cancer whose cancer had worsened after erlotinib treatment. The goal was to find a safe dose and see if the combination could shrink tumors. This is a disease control study, not a cure, as ongoing management is needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Case Western Reserve University

    Cleveland, Ohio, 44106, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Georgetown University/Lombardi Comprehensive Cancer Center

    Washington D.C., District of Columbia, 20007, United States

  • Katmai Oncology Group

    Anchorage, Alaska, 99508, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Park Nicollet Institute

    Saint Louis Park, Minnesota, 55416, United States

  • Stanford University Medical Center

    Palo Alto, California, 94305, United States

  • Summit Medical Group

    Berkeley Heights, New Jersey, 07922, United States

  • Swedish Cancer Institute

    Seattle, Washington, 98104, United States

  • University of California, Davis

    Sacramento, California, 95817, United States

  • University of Chicago Medical Center

    Chicago, Illinois, 60637, United States

  • University of Washington/ Seattle Cancer Care Alliance

    Seattle, Washington, 98109, United States

  • Yale University School of Medicine

    New Haven, Connecticut, 06520, United States