Daily Anti-Inflammatories may shield spines in ankylosing spondylitis patients on biologics

NCT ID NCT02469753

First seen May 23, 2026 · Last updated May 23, 2026

Summary

This study looked at whether taking non-steroidal anti-inflammatory drugs (NSAIDs) every day, along with anti-TNF therapy, can prevent new bone growth in the spine of people with ankylosing spondylitis. About 188 adults with active disease were randomly assigned to continuous NSAIDs or on-demand use. The goal was to see if daily NSAIDs reduce spinal damage seen on X-rays over time.

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Contacts and locations

Locations

  • Service de Rhumatologie - CHU de Bordeaux

    Bordeaux, France

  • Service de rhumatologie - AP-HP - Hôpital Lariboisière

    Paris, France

  • Service de rhumatologie - CHU d'Amiens

    Amiens, France

  • Service de rhumatologie - CHU de Besançon

    Besançon, France

  • Service de rhumatologie - CHU de Brest

    Brest, France

  • Service de rhumatologie - CHU de Nice

    Nice, France

  • Service de rhumatologie - CHU de Tours

    Tours, France

  • service de Rhumatologie - CH Princesse Grace

    Monaco, Monaco

  • service de rhumatologie - AP-HP - Hôpital Ambroise Paré

    Boulogne-Billancourt, France

  • service de rhumatologie - AP-HP - Hôpital Henri Mondor

    Paris, France

  • service de rhumatologie - AP-HP- Hôpital La Pitié Salpétrière

    Paris, France

  • service de rhumatologie - CH Le Mans

    Le Mans, France

  • service de rhumatologie - CH de Cahors

    Cahors, France

  • service de rhumatologie - CHR d'Orléans

    Orléans, France

  • service de rhumatologie - CHU de Limoges

    Limoges, France

  • service de rhumatologie - CHU de Montpellier

    Montpellier, France

  • service de rhumatologie - CHU de Nancy

    Nancy, France

  • service de rhumatologie - CHU de Rouen

    Rouen, France

  • service de rhumatologie - CHU de Saint-Etienne

    Saint-Etienne, France

  • service de rhumatologie - CHU de Strasbourg

    Strasbourg, France

  • service de rhumatologie - CHU de Toulouse

    Toulouse, France

  • service de rhumatologuie - CH de Pau

    Pau, France

Conditions

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