Painkiller showdown: which is safer for your heart when you already take aspirin?

This study looked at how two common pain relievers—celecoxib (a Coxib) and naproxen (an NSAID)—affect blood clotting in people with rheumatoid arthritis who also take daily aspirin for heart health. Eight adults with arthritis and increased heart risk took each pain reliever for four weeks in a random order. The goal was to see if one pain reliever interfered more with aspirin's ability to prevent blood clots. The study was terminated early, so results are limited.