Laser zaps small breast tumors, no scalpel needed

NCT ID NCT03463954

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a laser device called Novilase that destroys small breast tumors (≤15 mm) using heat, without cutting them out. About 122 women will receive the laser treatment, and researchers will check if it works as well as standard lumpectomy. The goal is to see if this less invasive approach can reduce the need for repeat procedures and speed up recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Novilase laser ablation device

What this could lead to

If successful, this could offer a non-surgical option for small breast tumors, with quicker recovery and less scarring than lumpectomy.

What could go wrong

This is a mid-stage study with 122 participants, so results may not apply to everyone. Risks include incomplete ablation, infection, or cosmetic issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Breast Centre Zurich

    TERMINATED

    Zurich, 8008, Switzerland

  • Buffalo General Medical Center

    RECRUITING

    Buffalo, New York, 14203, United States

    Contact Email: •••••@•••••

    Contact

  • Charing Cross Hospital, Imperial College Healthcare NHS Trust

    RECRUITING

    London, United Kingdom

    Contact

    Contact

    Contact

  • Churchill Hospital, Oxford University Hospitals NHS Trust

    RECRUITING

    Oxford, United Kingdom

    Contact

    Contact

    Contact

  • City of Hope

    WITHDRAWN

    Duarte, California, 91010, United States

  • Eisenhower Health

    RECRUITING

    Rancho Mirage, California, 92270, United States

    Contact

  • Ichilov | Tel Aviv Sourasky Medical Center

    RECRUITING

    Tel Aviv, Israel

    Contact

  • St. Elisabeth-Krankenhaus Köln-Hohenlind

    RECRUITING

    Cologne, 50935, Germany

    Contact

  • Summit Health

    NOT_YET_RECRUITING

    Florham Park, New Jersey, 07932, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UC San Diego Health

    RECRUITING

    La Jolla, California, 92037, United States

    Contact

  • University Hospital Zurich

    RECRUITING

    Zurich, 8091, Switzerland

    Contact

  • Walter Reed National Military Medical Center

    WITHDRAWN

    Bethesda, Maryland, 20889, United States

  • Yale University

    RECRUITING

    New Haven, Connecticut, 06511, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact