Study reveals hidden dangers of common antidepressant in seniors with kidney disease

NCT ID NCT07527481

First seen Apr 26, 2026 · Last updated May 15, 2026 · Updated 5 times

Summary

This study examined health records of 5,000 older adults with low kidney function who started taking nortriptyline, an antidepressant. Researchers compared those on higher doses (over 10 mg/day) to those on a low dose (10 mg/day) to see if they had more emergency visits, hospital stays, or deaths within 30 days. The goal was to understand if dose adjustments are needed for this vulnerable group.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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