Tailoring blood pressure drugs by body weight could prevent dangerous drops during c-sections
NCT ID NCT07706426
First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time
Summary
This study looks at whether a woman's body mass index (BMI) changes the amount of norepinephrine needed to prevent low blood pressure after spinal anesthesia for a C-section. Researchers will give different doses of norepinephrine to pregnant women with various BMIs and monitor how many develop low blood pressure. The goal is to find the safest and most effective dose for each body type.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- norepinephrine infusion at doses of 0.025, 0.05, 0.075, and 0.1 micrograms per kilogram per minute
- What this could lead to
- If successful, this could help doctors tailor norepinephrine doses to a woman's body size, reducing dangerous drops in blood pressure during C-sections.
- What could go wrong
- This is a small, early-phase study with only 80 participants, so results may not apply to all women. Norepinephrine can cause high blood pressure or slow heart rate as side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ain Shams
Cairo, Abbasia, 00202, Egypt
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