Heart stent showdown: one branch or two?

NCT ID NCT00376571

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at the best way to use drug-eluting stents (tiny mesh tubes that release medication) in patients with coronary artery disease where the blockage is at a fork (bifurcation). 413 patients were randomly assigned to get stents in both branches of the fork or only in the main branch, with optional treatment of the side branch. The goal was to see which approach reduces the risk of heart-related death, heart attack, stent clotting, or the need for repeat procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

drug-eluting stent

What this could lead to

If successful, this could help doctors choose the safest and most effective stenting strategy for patients with blocked arteries at a fork (bifurcation).

What could go wrong

This is a completed Phase 4 trial with 413 patients, so results are already known. The findings may not apply to all types of blockages or newer stents.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Skejby Hospital, University of Aarhus

    Aarhus, 8200, Denmark