Can a simple infusion stop blood pressure crashes during sepsis surgery?

NCT ID NCT07022730

Completed Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether giving the drug noradrenaline before anesthesia can prevent dangerous low blood pressure in patients with sepsis undergoing surgery. Eighty adults took part, and researchers measured how many experienced a drop in blood pressure after being put to sleep. The goal is to find a simple way to make surgery safer for these very sick patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: noradrenaline
What this could lead to: If it works, this could provide a simple way to prevent dangerous drops in blood pressure during surgery for sepsis patients, potentially reducing complications.
What could go wrong: This is a small, single-center trial (80 people) testing a common drug for a new purpose. Results may not apply to all sepsis patients, and the drug itself can cause side effects like high blood pressure or heart strain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hypotensive disorder infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST-INDUCTION HYPOTENSION SEPSIS

Contacts and locations

Locations

Cairo University

Cairo, Cairo Governorate, 6890, Egypt

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