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New brush and slurry combo could save failing dental implants

NCT ID NCT06695559

Completed Disease control Sponsor: Aristotle University Of Thessaloniki Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a non-surgical treatment for peri-implantitis, a gum infection around dental implants. Forty adults with mild bone loss received either a cleaning with a special chitosan brush alone or with an added tetracycline antibiotic slurry. The goal was to see if the antibiotic slurry improves healing and reduces pocket depth around the implant.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
chitosan brush and tetracycline slurry
What this could lead to
If successful, this could offer a better non-surgical option to control peri-implantitis and reduce the need for more invasive procedures.
What could go wrong
This is a small, early-phase trial with only 40 participants, so results may not apply widely. The treatment is for mild cases and may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Peri-Implantitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIIMPLANT DISEASES PERIIMPLANTITIS

Contacts and locations

Locations

  • Aristotle University of Thessaloniki

    Thessaloniki, 54124, Greece

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