Knee replacement avoided? study tests 3-Month exercise and diet program

NCT ID NCT06623149

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Marius Henriksen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a 3-month non-surgical program—including patient education, supervised exercise, and diet counseling—can help people with knee osteoarthritis avoid knee replacement surgery while maintaining their quality of life. Researchers will follow 2,500 patients referred for knee surgery in Denmark over two years. The goal is to see if this approach reduces the number of surgeries without harming patients' well-being.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Non-surgical management program (education, exercise, weight loss counseling)

What this could lead to

If successful, this could show that many knee replacements can be safely avoided with a structured non-surgical program, improving patient outcomes and reducing healthcare costs.

What could go wrong

This is an observational study, not a randomized trial, so results may be influenced by patient selection. The program may not work for everyone, and some patients may still need surgery.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

agnosia Motor Activity osteoarthritis osteoarthritis, knee Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Amager Hvidovre Hospital

    Copenhagen, Hvidovre, 2650, Denmark

  • Bispebjerg Frederiksberg Hospital

    Copenhagen, Copenhagen, 2000, Denmark

  • Bornholms hospital

    Rønne, Denmark

  • Nordsjællands Hospital

    Hillerød, 3400, Denmark

  • Rigshospitalet

    Copenhagen, 2100, Denmark

  • herlev Gentofe Hospital

    Copenhagen, 2730, Denmark