New blood tests could replace painful liver biopsies for millions with fatty liver disease
NCT ID NCT03695796
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looked at over 1,000 people with non-alcoholic fatty liver disease (NAFLD) to see if simple blood tests and ultrasound-based devices can accurately detect liver scarring (fibrosis) without needing a liver biopsy. The goal is to develop reliable, non-invasive tools to identify patients who may benefit from future treatments. Participants had liver biopsies to confirm their condition and also underwent various non-invasive tests for comparison.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to reliable non-invasive tests to identify NAFLD patients who need treatment, avoiding the need for liver biopsies.
What could go wrong
This is an observational study, not a treatment trial. The tests may not be accurate enough to replace biopsy in all cases, and results may not apply to all patient groups.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Amiens University Hospital
Amiens, France
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Edouard Herriot Hospital
Lyon, France
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Grenoble University Hospital
Grenoble, France
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Hospital Center Of Lorient
Lorient, France
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Hospital of Le Havre
Le Havre, France
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Saint-Joseph Hospital
Marseille, France
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University Hospital Of Nancy
Vandœuvre-lès-Nancy, France
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University Hospital Of Nice
Nice, France
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University Hospital of Besançon
Besançon, France
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University Hospital of Clermont-Ferrand
Clermont-Ferrand, France
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University Hospital of Lille
Lille, France
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University Hospital of Pointe à Pitre
Pointe-à-Pitre, Guadeloupe
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University Hospital of Rouen
Rouen, France
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University Hospital of Strasbourd
Strasbourg, France
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University Hospital of Toulouse
Toulouse, France
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University of Bordeaux
Pessac, France