Wheat sensitivity: a lifelong sentence or just a phase?

NCT ID NCT02823522

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study followed 280 people previously diagnosed with non-celiac wheat sensitivity to see if they still needed to avoid wheat years later. Researchers used questionnaires and, in some cases, a double-blind wheat challenge to confirm if symptoms returned. The goal was to understand whether this condition is permanent or can resolve over time.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this study could clarify whether non-celiac wheat sensitivity is a lifelong condition or something people can outgrow.
What could go wrong
This is an observational follow-up, not a treatment trial, so it won't test any new therapy. Results may not apply to all people with similar symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Internal Medicine, Giovanni Paolo II Hospital of Sciacca

    Sciacca, Agrigento, 92019, Italy

  • Department of Internal Medicine, University Hospital of Palermo

    Palermo, Palermo, 90129, Italy

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