Wheat sensitivity: a lifelong sentence or just a phase?
NCT ID NCT02823522
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study followed 280 people previously diagnosed with non-celiac wheat sensitivity to see if they still needed to avoid wheat years later. Researchers used questionnaires and, in some cases, a double-blind wheat challenge to confirm if symptoms returned. The goal was to understand whether this condition is permanent or can resolve over time.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- What this could lead to
- If successful, this study could clarify whether non-celiac wheat sensitivity is a lifelong condition or something people can outgrow.
- What could go wrong
- This is an observational follow-up, not a treatment trial, so it won't test any new therapy. Results may not apply to all people with similar symptoms.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Internal Medicine, Giovanni Paolo II Hospital of Sciacca
Sciacca, Agrigento, 92019, Italy
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Department of Internal Medicine, University Hospital of Palermo
Palermo, Palermo, 90129, Italy
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