Wheat sensitivity: a lifelong sentence or just a phase?

NCT ID NCT02823522

First seen May 06, 2026 · Last updated Jun 21, 2026 · Updated 10 times

Summary

This study followed 280 people previously diagnosed with non-celiac wheat sensitivity to see if they still needed to avoid wheat years later. Researchers used questionnaires and, in some cases, a double-blind wheat challenge to confirm if symptoms returned. The goal was to understand whether this condition is permanent or can resolve over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Department of Internal Medicine, Giovanni Paolo II Hospital of Sciacca

    Sciacca, Agrigento, 92019, Italy

  • Department of Internal Medicine, University Hospital of Palermo

    Palermo, Palermo, 90129, Italy

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could clarify whether non-celiac wheat sensitivity is a lifelong condition or something people can outgrow.

What could go wrong

This is an observational follow-up, not a treatment trial, so it won't test any new therapy. Results may not apply to all people with similar symptoms.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.