New surgical audit aims to reduce arm swelling in breast cancer patients

NCT ID NCT07085442

Recruiting now Knowledge-focused Sponsor: University Hospitals of Derby and Burton NHS Foundation Trust Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is auditing a surgical technique called Targeted Sentinel Node Biopsy (TSNB) for breast cancer patients who have a small number of cancer cells in their lymph nodes. The goal is to see if this less invasive procedure can accurately identify cancer spread while causing less arm swelling than traditional lymph node removal. Researchers will track outcomes in 300 patients across the UK.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Targeted Sentinel Node Biopsy (TSNB) - a surgical procedure
What this could lead to: If successful, this could show that TSNB is a safe and effective way to stage breast cancer, potentially reducing the need for more extensive lymph node removal and lowering the risk of arm swelling.
What could go wrong: This is an observational audit, not a treatment trial, so it won't directly test a new therapy. Results may not change practice immediately, and the procedure's accuracy depends on surgeon skill and patient selection.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm metastatic malignant neoplasm in the lymph nodes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AXILLA; BREAST AXILLARY LYMPH NODES DISSECTION AXILLARY METASTASES AXILLARY ULTRASOUND BREAST CANCER NODE-POSITIVE BREAST CANCER SENTINEL LYMPH NODE BIOPSY (SLNB)

Contacts and locations

Locations

Addenbrooke's Hospital
RECRUITING

Cambridge, United Kingdom
Burnley General Teaching Hospital
RECRUITING

Burnley, United Kingdom
Gartnavel General Hospital
RECRUITING

Glasgow, United Kingdom
Liverpool University Hospitals NHS Foundation Trust
RECRUITING

Liverpool, United Kingdom
Mersey and West Lancashire Teaching Hospitals
RECRUITING

St Helens, United Kingdom
Royal Alexandra Hospital
RECRUITING

Paisley, United Kingdom
The Royal Wolverhampton NHS Trust
RECRUITING

Wolverhampton, WV10 0QP, United Kingdom
The Shrewsbury and Telford Hospital NHS Trust
RECRUITING

Shrewsbury, United Kingdom
University Hospital of North Tees and Hartlepool
RECRUITING

Stockton-on-Tees, United Kingdom
University Hospitals of Derby and Burton
RECRUITING

Derby, United Kingdom
Warrington and Halton Teaching Hospitals
RECRUITING

Warrington, United Kingdom
Wycombe Hospital
RECRUITING

High Wycombe, HP11 2TT, United Kingdom

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