New hope for tough leukemia: experimental drug targets resistant cancers

NCT ID NCT06549790

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug, NMS-03597812, in adults with acute myeloid leukemia that has come back or not responded to standard treatments. The goal is to find a safe dose and see if the drug can shrink or control the cancer. About 124 people will take part, including those with a specific gene change (TP53 mutation) that often makes the disease harder to treat.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Blood and Marrow Transplant Group of Georgia

    RECRUITING

    Atlanta, Georgia, 30342, United States

  • City of Hope - Duarte

    RECRUITING

    Duarte, California, 91010, United States

  • Gabrail Cancer Research Center

    RECRUITING

    Canton, Ohio, 44718, United States

  • Mayo Clinic Cancer Center (MCCC) - Rochester

    WITHDRAWN

    Rochester, Minnesota, 55905, United States

  • Medical Oncology Hematology Consultants

    RECRUITING

    Newark, Delaware, 19713, United States

  • Rocky Mountain Cancer Centers

    RECRUITING

    Aurora, Colorado, 80012, United States

  • The University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States