New hope for tough leukemia: experimental drug targets resistant cancers
NCT ID NCT06549790
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 22 times
Summary
This early-stage study tests an experimental drug called NMS-03597812 in about 124 adults whose acute myeloid leukemia has returned or not responded to standard treatments, including those with a TP53 gene mutation. The main goals are to check the drug's safety, find the right dose, and see if it can shrink or control the cancer. Participants will receive the drug alone initially, with a possible future addition of another drug (venetoclax).
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Blood and Marrow Transplant Group of Georgia
RECRUITINGAtlanta, Georgia, 30342, United States
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City of Hope - Duarte
RECRUITINGDuarte, California, 91010, United States
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Gabrail Cancer Research Center
RECRUITINGCanton, Ohio, 44718, United States
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Mayo Clinic Cancer Center (MCCC) - Rochester
WITHDRAWNRochester, Minnesota, 55905, United States
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Medical Oncology Hematology Consultants
RECRUITINGNewark, Delaware, 19713, United States
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Rocky Mountain Cancer Centers
RECRUITINGAurora, Colorado, 80012, United States
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The University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Conditions
Explore the condition pages connected to this study.