Risdiplam's hidden benefit: fixing Nerve-Muscle links in SMA

NCT ID NCT05219487

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at 18 adults with spinal muscular atrophy (SMA) who had taken the oral medication risdiplam for at least one year. Researchers measured how well nerves and muscles communicate by using electrical stimulation tests. The goal was to see if risdiplam improves these connections compared to historical data. This was an observational study, meaning participants received their usual treatment, and no new drugs were tested.

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Conditions

The condition(s) this trial relates to.

spinal muscular atrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Ohio State University Wexner Medical Center

    Columbus, Ohio, 43210, United States