New pill aims to ease muscle weakness in rare nerve disease

NCT ID NCT06414954

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tests an experimental pill called NMD670 in 84 adults with myasthenia gravis, a condition that causes muscle weakness. Participants take the pill or a placebo twice daily for 21 days. Researchers will measure changes in muscle strength and daily activities to see if the drug helps control symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

NMD670 (tablet taken twice daily)

What this could lead to

If it works, this could point toward a new daily pill to help control muscle weakness in myasthenia gravis.

What could go wrong

This is an early Phase 2 trial with only 84 people over 21 days. It may not show clear benefit, and side effects are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MYASTHENIA GRAVIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

myasthenia gravis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AOU Pisana

    RECRUITING

    Pisa, 56126, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • ASST Papa Giovanni XXIII (Azienda Ospedaliera Papa Giovanni XXIII)

    RECRUITING

    Bergamo, 21127, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Aarhus University Hospital

    RECRUITING

    Aarhus, Denmark

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Augusta University, Neuroscience Center

    RECRUITING

    Augusta, Georgia, 30912, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Azienda Ospedaliera Sant'Andrea - Universita di Roma La Sapienza

    RECRUITING

    Roma, 00189, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de Nice

    RECRUITING

    Nice, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Hospitalier Universitaire de Nantes - Hôtel Dieu Centre de Référence des Maladies Neuromusculaires Rares -

    RECRUITING

    Nantes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre de Référence des Maladies Neuromusculaires et de la SLA

    RECRUITING

    Marseille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre de référence des maladies neuromusculaires AOC-CHU de Bordeaux - Hôpital Pellegrin

    RECRUITING

    Bordeaux, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centro Sclerosi Multipla Napoli - AOU Vanvitelli

    RECRUITING

    Naples, 80138, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centrum Medyczne Hope Clinic

    RECRUITING

    Lublin, 20701, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centrum Medyczne Neuro Protect

    RECRUITING

    Warsaw, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • DIMER, IRCCS, Ospedale San Raffaele

    RECRUITING

    Milan, Italy

    Contact

    Contact Email: •••••@•••••

  • Galen Clinic

    RECRUITING

    Lublin, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospìtal Universitari Vall d'Hebrón

    RECRUITING

    Barcelona, Spain

    Contact Email: •••••@•••••

    Contact

  • IRCCS Fondazione Istituto Neurologico Carlo Besta, Dipartimento di Ricerca e Sviluppo clinico

    RECRUITING

    Milan, 20133, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • IRCCS Istituo delle Scienze neurologiche di Bologna, UOC Clinica neurologica Ospedale

    RECRUITING

    Bologna, 40139, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • IRCCS Ospedale Policlinico San Martino

    RECRUITING

    Genova, 16132, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • JSC Curatio

    ACTIVE_NOT_RECRUITING

    Tbilisi, Georgia

  • LTD David Tatishvili Health Center

    ACTIVE_NOT_RECRUITING

    Tbilisi, Georgia

  • Leiden Universitair Medisch Centrum (LUMC)

    RECRUITING

    Leiden, 2333, Netherlands

    Contact Email: •••••@•••••

    Contact

  • Ltd New Hospitals

    ACTIVE_NOT_RECRUITING

    Tbilisi, Georgia

  • NeuroCor Banaszkiewicz, Tomaszewski Lekarze Spółka Partnerska

    RECRUITING

    Myślenice, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Neurologia Śląska Centrum Medyczne

    RECRUITING

    Katowice, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Neuromuscular Research Division | University of South Florida

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • NextGen Precision Health

    RECRUITING

    Columbia, Missouri, 65212, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Profound Research LLC

    WITHDRAWN

    Carlsbad, California, 92011, United States

  • Rigshospitalet University of Copenhagen

    RECRUITING

    Copenhagen, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • SFM Clinical Research, LLC

    RECRUITING

    Boca Raton, Florida, 33487, United States

    Contact Phone: •••-•••-••••

    Contact

  • Semmes Murphey Clinic

    RECRUITING

    Memphis, Tennessee, 38120, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie sp.z o.o

    RECRUITING

    Krakow, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Ohio State University

    RECRUITING

    Columbus, Ohio, 43221, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UZ Leuven

    WITHDRAWN

    Leuven, Belgium

  • Unité de Recherche Clinique NeuroSciences

    RECRUITING

    Nice, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Clinical Center Nis, Neurology Clinic

    RECRUITING

    Niš, Serbia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Clinical Center of Serbia, Neurology Clinic

    WITHDRAWN

    Belgrade, Serbia

  • University of California Irvine Medical Center

    RECRUITING

    Irvine, California, 92868, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Colorado Neuromuscular Division

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Oregon

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact