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New pill aims to ease muscle weakness in rare nerve disease

NCT ID NCT06414954

Recruiting now Disease control Sponsor: NMD Pharma A/S Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study tests an experimental pill called NMD670 in 84 adults with myasthenia gravis, a condition that causes muscle weakness. Participants take the pill or a placebo twice daily for 21 days. Researchers will measure changes in muscle strength and daily activities to see if the drug helps control symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
NMD670 (tablet taken twice daily)
What this could lead to
If it works, this could point toward a new daily pill to help control muscle weakness in myasthenia gravis.
What could go wrong
This is an early Phase 2 trial with only 84 people over 21 days. It may not show clear benefit, and side effects are still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

myasthenia gravis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MYASTHENIA GRAVIS MYASTHENIA GRAVIS, MUSK

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • AOU Pisana

    RECRUITING

    Pisa, 56126, Italy

  • ASST Papa Giovanni XXIII (Azienda Ospedaliera Papa Giovanni XXIII)

    RECRUITING

    Bergamo, 21127, Italy

  • Aarhus University Hospital

    RECRUITING

    Aarhus, Denmark

  • Augusta University, Neuroscience Center

    RECRUITING

    Augusta, Georgia, 30912, United States

  • Azienda Ospedaliera Sant'Andrea - Universita di Roma La Sapienza

    RECRUITING

    Roma, 00189, Italy

  • CHU de Nice

    RECRUITING

    Nice, France

  • Centre Hospitalier Universitaire de Nantes - Hôtel Dieu Centre de Référence des Maladies Neuromusculaires Rares -

    RECRUITING

    Nantes, France

  • Centre de Référence des Maladies Neuromusculaires et de la SLA

    RECRUITING

    Marseille, France

  • Centre de référence des maladies neuromusculaires AOC-CHU de Bordeaux - Hôpital Pellegrin

    RECRUITING

    Bordeaux, France

  • Centro Sclerosi Multipla Napoli - AOU Vanvitelli

    RECRUITING

    Naples, 80138, Italy

  • Centrum Medyczne Hope Clinic

    RECRUITING

    Lublin, 20701, Poland

  • Centrum Medyczne Neuro Protect

    RECRUITING

    Warsaw, Poland

  • DIMER, IRCCS, Ospedale San Raffaele

    RECRUITING

    Milan, Italy

  • Galen Clinic

    RECRUITING

    Lublin, Poland

  • Hospìtal Universitari Vall d'Hebrón

    RECRUITING

    Barcelona, Spain

  • IRCCS Fondazione Istituto Neurologico Carlo Besta, Dipartimento di Ricerca e Sviluppo clinico

    RECRUITING

    Milan, 20133, Italy

  • IRCCS Istituo delle Scienze neurologiche di Bologna, UOC Clinica neurologica Ospedale

    RECRUITING

    Bologna, 40139, Italy

  • IRCCS Ospedale Policlinico San Martino

    RECRUITING

    Genova, 16132, Italy

  • JSC Curatio

    ACTIVE_NOT_RECRUITING

    Tbilisi, Georgia

  • LTD David Tatishvili Health Center

    ACTIVE_NOT_RECRUITING

    Tbilisi, Georgia

  • Leiden Universitair Medisch Centrum (LUMC)

    RECRUITING

    Leiden, 2333, Netherlands

  • Ltd New Hospitals

    ACTIVE_NOT_RECRUITING

    Tbilisi, Georgia

  • NeuroCor Banaszkiewicz, Tomaszewski Lekarze Spółka Partnerska

    RECRUITING

    Myślenice, Poland

  • Neurologia Śląska Centrum Medyczne

    RECRUITING

    Katowice, Poland

  • Neuromuscular Research Division | University of South Florida

    RECRUITING

    Tampa, Florida, 33612, United States

  • NextGen Precision Health

    RECRUITING

    Columbia, Missouri, 65212, United States

  • Profound Research LLC

    WITHDRAWN

    Carlsbad, California, 92011, United States

  • Rigshospitalet University of Copenhagen

    RECRUITING

    Copenhagen, Denmark

  • SFM Clinical Research, LLC

    RECRUITING

    Boca Raton, Florida, 33487, United States

  • Semmes Murphey Clinic

    RECRUITING

    Memphis, Tennessee, 38120, United States

  • Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie sp.z o.o

    RECRUITING

    Krakow, Poland

  • The Ohio State University

    RECRUITING

    Columbus, Ohio, 43221, United States

  • The University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

  • UZ Leuven

    WITHDRAWN

    Leuven, Belgium

  • Unité de Recherche Clinique NeuroSciences

    RECRUITING

    Nice, France

  • University Clinical Center Nis, Neurology Clinic

    RECRUITING

    Niš, Serbia

  • University Clinical Center of Serbia, Neurology Clinic

    WITHDRAWN

    Belgrade, Serbia

  • University of California Irvine Medical Center

    RECRUITING

    Irvine, California, 92868, United States

  • University of Colorado Neuromuscular Division

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Email: •••••@•••••

  • University of Oregon

    RECRUITING

    Portland, Oregon, 97239, United States

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