Could a new drug help keep myasthenia gravis symptoms at bay?

NCT ID NCT07673744

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study tests whether ublituximab, given as an infusion, can help adults with myasthenia gravis maintain symptom control after initial treatment with efgartigimod. Participants will receive either ublituximab or a placebo, and researchers will track how long it takes for symptoms to worsen. The goal is to see if ublituximab can delay or prevent flare-ups in this autoimmune disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ublituximab (BRIUMVI)

What this could lead to

If successful, this could provide a new maintenance option to help people with myasthenia gravis stay stable longer and delay symptom worsening.

What could go wrong

This is an early phase 2 trial with only 120 participants, so results may not apply to everyone. The drug may cause side effects or fail to show benefit over placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

myasthenia gravis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • TG Therapeutics Investigational Trial Site

    RECRUITING

    Colorado Springs, Colorado, 80919, United States

  • TG Therapeutics Investigational Trial Site

    RECRUITING

    Clearwater, Florida, 33761, United States