Can a new biosimilar match Neulasta's power to rebuild white blood cells?

NCT ID NCT07738991

First seen Jul 31, 2026 ยท Last updated Jul 31, 2026

Summary

This trial is testing whether an experimental drug called NKF-PEG works in the same way as the approved medicine Neulasta. Both are designed to help the body produce more white blood cells, which are important for fighting infection. Healthy adult male volunteers will receive a single injection of each drug at different times, and researchers will compare how the drugs are absorbed and how strongly they stimulate white blood cell production. The goal is to see if NKF-PEG could be a similar, potentially more affordable alternative to Neulasta.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
NKF-PEG (a pegfilgrastim biosimilar candidate) compared to US-Neulasta (pegfilgrastim)
What this could lead to
If NKF-PEG proves similar to Neulasta, it could become a more affordable option to help cancer patients recover white blood cell counts after chemotherapy.
What could go wrong
This is an early-stage trial in healthy volunteers, so results may not predict real-world effectiveness in patients. There are also risks like bone pain and allergic reactions.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ethics Committee of Hopeshine-Minsheng Hospital of Xinzheng, Zhengzhou,

    RECRUITING

    Zhengzhou, China

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