Scientists supercharge Kids' own immune cells to fight cancer
NCT ID NCT02573896
Summary
This early-stage study is testing a new combination treatment for children and young adults whose neuroblastoma has come back or hasn't responded to standard therapies. Doctors take a patient's own natural killer (NK) immune cells, grow large numbers of them in a lab, and then infuse them back along with two other drugs (dinutuximab and lenalidomide) to help the cells attack the cancer. The main goals are to see if this process is safe, figure out the best dose, and learn if the treatment shows signs of fighting the tumor.
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Contacts and locations
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Locations
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AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus
Atlanta, Georgia, 30322, United States
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C.S Mott Children's Hospital
Ann Arbor, Michigan, 48109, United States
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Children's Hospital Los Angeles
Los Angeles, California, 90027-0700, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104-4318, United States
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Childrens Hospital Boston, Dana-Farber Cancer Institute.
Boston, Massachusetts, 02115, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229-3039, United States
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Cook Children's Healthcare System
Fort Worth, Texas, 76104, United States
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Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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Seattle Children's Hospital
Seattle, Washington, 98105, United States
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UCSF Helen Diller Family Comprehensive Cancer Center
San Francisco, California, 94115, United States
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University of Chicago Comer Children's Hospital
Chicago, Illinois, 60637, United States
Conditions
Explore the condition pages connected to this study.