Can donor immune cells help fight pancreatic cancer after surgery?

NCT ID NCT06730009

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding donor natural killer (NK) cells to standard chemotherapy can help prevent cancer from coming back after surgery for pancreatic or bile duct cancer. About 42 adults who had their tumor removed will receive either chemotherapy alone or chemotherapy plus NK cell infusions. The trial first finds the safest dose of NK cells, then compares how long people stay cancer-free in each group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

donor natural killer (NK) cells combined with chemotherapy (S-1, leucovorin, oxaliplatin, gemcitabine)

What this could lead to

If it works, this could point toward a way to delay or prevent cancer recurrence after surgery for pancreatic or bile duct cancer.

What could go wrong

This is an early, small trial (42 people) testing a new cell therapy for the first time in humans. The added benefit over chemotherapy alone is unproven, and there may be unknown side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cholangiocarcinoma malignant pancreatic neoplasm pancreatic ductal adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Cheng Kung University Hospital

    RECRUITING

    Tainan, 138, Taiwan

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact