Triple threat: new combo therapy takes on tough prostate cancer

NCT ID NCT03543189

First seen Nov 01, 2025 · Last updated Jun 10, 2026 · Updated 34 times

Summary

This study tests whether adding the immunotherapy drug nivolumab to standard radiation and hormone therapy is safe and effective for men with a very aggressive type of prostate cancer (Gleason grade group 5). About 44 men will receive the combination treatment. The goal is to see if this approach can delay cancer progression and improve outcomes.

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Contacts and locations

Locations

  • H. Lee Moffitt Cancer Center and Research Institute

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.