New hope for Hard-to-Treat cancers: targeted immunotherapy trial launches

NCT ID NCT04957615

First seen Oct 31, 2025 · Last updated May 12, 2026 · Updated 23 times

Summary

This study tests whether the immunotherapy drug nivolumab can help control cancer in people with metastatic or inoperable solid tumors that have a specific genetic change (ARID1A mutation) and a protein marker (CXCL13). Sixteen participants will receive nivolumab to boost their immune system's ability to fight the cancer. The goal is to see if the tumors shrink or stop growing, and how long people live.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.