New hope for Hard-to-Treat cancers: targeted immunotherapy shows promise
NCT ID NCT04957615
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether the immunotherapy drug nivolumab can help control cancer in 16 people with advanced solid tumors that have spread or can't be removed by surgery. Participants must have a specific genetic change (ARID1A mutation) and a protein marker (CXCL13) in their tumors. The goal is to see if these markers can predict who will benefit from treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States