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New combo therapy shows promise for Hard-to-Treat blood cancers

NCT ID NCT01592370

Completed Disease control Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 32 times

Summary

This study tested the safety of the drug nivolumab, alone or combined with other drugs like daratumumab, in 320 people with blood cancers (lymphoma or multiple myeloma) that had returned or stopped responding to treatment. The main goal was to track serious side effects. This is not a cure, as patients may need ongoing treatment, but it helps understand how to better control these cancers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Abramson Cancer Center

    Philadelphia, Pennsylvania, 19104, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Division Of Hematology & Oncology Ctr. For Health Sciences

    Los Angeles, California, 90095, United States

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

  • Huntsman Cancer Institute At The Univ. Of Utah

    Salt Lake City, Utah, 84112, United States

  • John Theurer Cancer Center

    Hackensack, New Jersey, 07601, United States

  • Local Institution

    Yvoir, B-5530, Belgium

  • Local Institution

    Bologna, 40138, Italy

  • Local Institution

    Chorzów, 41-500, Poland

  • Local Institution - 0001

    New York, New York, 10065, United States

  • Local Institution - 0002

    Rochester, Minnesota, 55905, United States

  • Local Institution - 0003

    Baltimore, Maryland, 21231, United States

  • Local Institution - 0004

    Philadelphia, Pennsylvania, 19111, United States

  • Local Institution - 0005

    Salt Lake City, Utah, 84112, United States

  • Local Institution - 0006

    Portland, Oregon, 97239, United States

  • Local Institution - 0007

    Philadelphia, Pennsylvania, 19104, United States

  • Local Institution - 0009

    Boston, Massachusetts, 02215, United States

  • Local Institution - 0011

    Ann Arbor, Michigan, 48109, United States

  • Local Institution - 0012

    Los Angeles, California, 90095, United States

  • Local Institution - 0014

    Hackensack, New Jersey, 07601, United States

  • Local Institution - 0015

    Boston, Massachusetts, 02215, United States

  • Local Institution - 0017

    Aurora, Colorado, 80045, United States

  • Local Institution - 0018

    Westwood, Kansas, 66205, United States

  • Local Institution - 0019

    Indianapolis, Indiana, 46202, United States

  • Local Institution - 0023

    Orlando, Florida, 32804, United States

  • Local Institution - 0028

    Columbus, Ohio, 43210, United States

  • Local Institution - 0033

    Omaha, Nebraska, 68130, United States

  • Local Institution - 0035

    Clovis, California, 93611, United States

  • Local Institution - 0037

    Skokie, Illinois, 60077, United States

  • Local Institution - 0039

    Athens, 11528, Greece

  • Local Institution - 0040

    Poznan, 61-848, Poland

  • Local Institution - 0042

    Wroclaw, 50-367, Poland

  • Local Institution - 0043

    Poitiers, Vienne, 86021, France

  • Local Institution - 0044

    Nantes, 44000, France

  • Local Institution - 0045

    Ghent, 9000, Belgium

  • Local Institution - 0047

    Sint-Niklaas, 9100, Belgium

  • Local Institution - 0049

    Warsaw, 02-776, Poland

  • Local Institution - 013

    New Haven, Connecticut, 06520, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • OHSU Center for Hematologic Malignancies

    Portland, Oregon, 97239, United States

  • The Sidney Kimmel Comprehensive Cancer Center

    Baltimore, Maryland, 21231, United States

  • University Of Michigan Health System

    Ann Arbor, Michigan, 48109, United States

Conditions

Explore the condition pages connected to this study.

HODGKIN LYMPHOMA MULTIPLE MYELOMA NON-HODGKIN'S LYMPHOMA